Gene Reporter Systems
Promega ZAP70 Kinase Enzyme System
Recombinant full-length human ZAP70 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ZAP70 is a nonreceptor protein tyrosine kinase (part of the Syk/Zap70 family) that is involved in signaling by the T-cell antigen receptor.
Promega NanoBRET TE BET BRD DNA Bundle, 1 each
NanoBRET Target Engagement Assay Components are for use with all NanoBRET Target Engagement Assays.
Promega PKCδ Kinase Enzyme System
Recombinant full-length human PKC delta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Protein kinase C delta is a member of the protein kinase C (PKC) family of serine-threonine kinases.
Promega AMPK (A1/B1/G1) Kinase Enzyme System
Recombinant full-length human AMPK (combination of A1/B1/G1 subunits) was expressed by baculovirus in Sf9 insect cells using C-terminal His tags. AMPK is an important energy-sensing enzyme that monitors cellular energy status.
Promega FcgammaRIIa-H ADCP Reporter Bioassay, Complete Kit, 1 each
The FcgammaRIIa-H ADCP Reporter Bioassay is a biologically relevant MOA-based assay that can be used to measure the potency and stability of antibodies and other biologics that specifically bind and activate FcgammaRIIa.
Promega PD-1/PD-L1 Blockade Bioassay, 5X, 1 each
The PD-1/PD-L1 Blockade Bioassay is a biologically relevant MOA-based assay that can be used to measure the potency and stability of antibodies and other biologics designed to block the PD-1/PD-L1 interaction.
Promega Calpain-Glo™ Assay System
The Calpain-Glo™ Protease Assay is a homogeneous, luminescent assay that measures calpain 1 (μ) and 2 (m) activities
Promega Glo Lysis Buffer (GLB)
A proprietary formulation developed to promote rapid lysis (5 minutes) of cultured mammalian cells without scraping or freeze-thaw cycles.
Promega Luciferase Assay Systems
An extremely sensitive reagent for rapid quantitation of firefly luciferase. Can be used for assays in single-tube luminometers or in multiwell-plate luminometers with auto-injectors.
Promega CHK1 Kinase Enzyme System
Recombinant full-length human CHK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CHK1 was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle.
Promega LCK Kinase Enzyme System
Recombinant full-length human LCK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. LCK (p56lck) is a member of the src family of nonreceptor tyrosine kinases.
Promega mFcgammaRIV ADCC Reporter Bioassay, Core Kit 5X, 1 each
The mFcgammaRIV ADCC Reporter Bioassay is a biologically relevant MOA-based assay that can be used to measure the activity of mouse antibodies that specifically bind and activate FcgammaRIV.
Promega SRC Kinase Enzyme System
Recombinant full-length human SRC was expressed in E. coli cells using an N-terminal GST tag. SRC was originally identified as a transforming protein of the Rous sarcoma virus that had enzymatic ability to phosphorylate tyrosine in protein substrates.
Promega Control Ab, Anti-PD-1, 1 each
Control Ab, Anti-PD-1for use with the PD-1/PD-L1 Blockade Bioassay.
Promega ADP-Glo™ Kinase Assay + PKC alpha Kinase Enzyme System
Recombinant full-length human PKC alpha was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKC alpha is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases.